I always use Google for image search when i want to find an image of something, this is just the way it is (good example of first mover advantage for those of you who think the concept is over rated).
I don't know why I've never looked at anything else (though I do use Tom Gibara's Flickr color search when looking for a specific hue http://www.tomgibara.com/computer-vision/color-search/).
Anyway long story short, today I stumbled across the Microsoft Live - Image Search .
Wow way cool - you can scroll down rather than clicking 20 images at a time. You can also change the size of the images on the preview page (as little as 15 or as many as 70) AND when you click on the image you don't get that crappy Google interface with the image header box.
The best feature however is the scratch pad that allows you to drag your images to the right so you can compare.
Wow. They really have done an amazing job here. I cant comment on 'search' capabilities (found both searches really fast) but just on interface way better than Google image. Check it out you might find it becomes your favorite as well.